Dalam penanganan otomikosis, antifungal topikal dapat diberikan dalam bentuk tetes telinga ataupun krim. Otomikosis atau otitis eksterna fungal merupakan infeksi jamur pada kanalis auditori eksterna, liang telinga, membran timpani, hingga telinga tengah. Otomikosis memiliki korelasi dengan kondisi lingkungan seperti iklim yang panas dan lembab, penyalahgunaan antibiotik topikal pada telinga, dan imunodefisiensi. Mayoritas kasus otomikosis disebabkan oleh Aspergillus. Patogen terbanyak kedua adalah Candida.[1-4]
Pilihan penatalaksanaan otomikosis mencakup penggunaan obat topikal agen antifungal, keratolitik, dan antiseptik. Meski demikian, penatalaksanaan dan eradikasi fungal memiliki tantangan tersendiri, yakni tingkat rekurensi yang tinggi dan pemilihan jenis sediaan obat antifungal yang sesuai dengan kondisi klinis pasien.[2,5,6]
Prinsip Manajemen Otomikosis
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Referensi
1. Haq M, Deshmukh P, et al. Review of Recurrent Otomycosis and Clotrimazole in Its Treatment. Cureus. 2020;14(10):e30098 DOI:10.7759/cureus.30098
2. Lekha V. Sneha, Priyadarshini V. Neelima, et al. Mycology of otomycosis and the role of antifungal drops versus antifungal cream in the treatment of otomycosis: an observational study. Int J Otorhinolaryngol Head Neck Surg. 2021;7(8):1343-1346 DOI: https://dx.doi.org/10.18203/issn.2454-5929.ijohns20212784
3. El Said M M, Abdelgelil A S, et al. Evaluation of Different Methods for Management of Difficult Cases of Otomycosis. Nature and Science. 2019;17(12):51-58
4. Nipa KK et al. Prevalence and Clinicomycological Studies of Otomycosis: A Review. J. Bio-Sci.2020;28:121-135 DOI: https://doi.org/10.3329/jbs.v28i0.44718
5. Praveen S V, Munagala K, et al. Efficacy of 7.5% povidone-iodine and 1% clotrimazole in the treatment of otomycosis – A prospective randomized study. Natl J Physiol Pharm Pharmacol. 2022;12(08):1142-1146 DOI:10.5455/njppp.2022.12.12451202124122021
6. Tan H, et al. Fungal otitis externa and tympanic membrane perforation: four-year experience at a Victorian hospital. Aust J Otolaryngol. 2021;4(28):1-7 DOI: https://dx.doi.org/10.21037/ajo-21-10
7. Sudrajad H, et al. Efektivitas asam asetat 2% dalam alkohol 70% dibanding ketokonazol 2% topikal pada terapi otomikosis. ORLI. 2018;48(1):26-33
8. Khan M A, Anwar B, et al. Comparison of Isoconazole Nitrate versus Nystatin for Treatment of Otomycosis. Pak Armed Forces Med J. 2021;71:S581-584 DOI: https://doi.org/10.51253/pafmj.v1i1.7949
9. Nemati S, Gerami H, et al. Sertaconazole versus Clotrimazole and Miconazole Creams in the Treatment of Otomycosis: A Placebo-Controlled Clinical Trial. Iranian Journal of Otorhinolaryngology. 2020;34(1):27-34 DOI:10.22038/IJORL.2021.54805.2872
10. Merza H, Abdulkhaleq J. Evaluation of the Prevalence of Otomycosis in Patients Referred to the ENT Clinic International Journal of Otolaryngology and Head & Neck Surgery. 2021;10:392-397 DOI: 10.4236/ijohns.2021.105036
11. Mishra P, Sachdeva S, et al. Otomycosis treatment: Topical Drops versus Cream – A prospective randomized study. Otomycosis treatment: Topical Drops versus Cream – A prospective randomized study. Arch Otolaryngol Rhinol. 2017;3(3):106-108 DOI: http://doi.org/10.17352/2455-1759.000059
12. Kiakojuri K, Rajabnia R, et al. Role of Clotrimazole in Prevention of Recurrent Otomycosis. Hindawi BioMed Research International. 2019;5269535:1-6 DOI: https://doi.org/10.1155/2019/5269535
13. Wu S, Cheng Y, et al. A Comparison of Antifungal Drugs and Traditional Antiseptic Medication for Otomycosis Treatment: A Systematic Review and Meta-Analysis. Front. Surg. 2021;8:739360 DOI:10.3389/fsurg.2021.739360
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