Obat Topikal untuk Pencegahan dan Penanganan Striae Gravidarum

Oleh :

dr.Gloscindy Arma Occifa

Striae gravidarum atau stretch marks sering menjadi keluhan wanita hamil atau setelah melahirkan, sehingga dokter sebaiknya mengetahui cara pencegahan maupun penangananya. Striae gravidarum merupakan skar atrofi berbentuk linier yang dialami oleh 55−90% wanita hamil, yang dapat muncul di area perut, payudara, punggung, panggul, paha, selangkangan, atau ketiak.[1-2]

Sekilas Mengenai Striae Gravidarum

Pada awal kemunculannya, striae gravidarum terlihat berwarna merah muda hingga merah dan tanpa indurasi, serta dapat menimbulkan rasa gatal atau sensasi terbakar. Fase ini disebut striae rubra atau immature striae. Semakin lama, striae rubra akan meninggi, memanjang, dan meluas menjadi berwarna merah keunguan. Setelah beberapa bulan, warna striae memudar menjadi hipopigmentasi dan berkerut. Fase ini disebut striae alba atau mature striae.[3-4]

(Konten ini khusus untuk dokter. Registrasi untuk baca selengkapnya)

Referensi

1. Kocaoz S, Beser NG, Kizilirmak A. Striae gravidarum in primigravida women: Prevalence, risk factors, prevention interventions and body image. J Matern Fetal Neonatal Med. 2019:1-7. doi:10.1080/14767058.2019.1591363
2. Yu Y, Wu H, Yin H, Lu Q. Striae gravidarum and different modalities of therapy: A review and update. J Dermatolog Treat. 2020:1-9. doi:10.1080/09546634.2020.1825614
3. Farahnik B, Park K, Kroumpouzos G, Murase J. Striae gravidarum: Risk factors, prevention, and management. Int J Womens Dermatol. 2017;3(2):77-85. doi:10.1016/j.ijwd.2016.11.001
4. Ud-Din S, McGeorge D, Bayat A. Topical management of striae distensae (stretch marks): Prevention and therapy of striae rubrae and albae. I Eur Acad Dermatol Venerol. 2016;30(2):211-222. doi:10.1111/jdv.13223
5. Motosko CC, Bieber AK, Pomeranz MK, Stein JA, Martires KJ. Physiologic changes of pregnancy: A review of the literature. Int J Womens Dermatol. 2017;3(4):219-224. doi:10.1016/j.ijwd.2017.09.003
6. Ersoy E, Ersoy AO, Celik EY, Tokmak A, Ozler S, et al. Is it possible to prevent striae gravidarum? Journal of the Chinese Medical Association. 2015;79(5):272-275. doi:10.1016/j.jcma.2015.12.007
7. Oakley AM, Patel BC. Stretch marks. Treasure Island (FL): StatPearls Publishing. 2023. https://www.ncbi.nlm.nih.gov/books/NBK436005/
8. Brennan M, Clarke M, Devane D. The use of anti stretch marks' products by women in pregnancy: A descriptive, cross-sectional survey. BMC Pregnancy Childbirth. 2016;16(1):276. doi: 10.1186/s12884-016-1075-9
9. Lokhande AJ, Mysore V. Striae distensae treatment review and update. Indian Dermatol Online J. 2019;10(4):380-395. doi: 10.4103/idoj.IDOJ_336_18
10. Rangel O, Arias I, Garcia E, Lopez-Padilla S. Topical tretinoin 0,1% for pregnancy-related abdominal striae: An open-label, multicenter, prospective study. Adv Ther. 2001;18(4):181-186. doi:10.1007/BF02850112
11. Pribanich S, Simpson FG, Held B, Yarbrough CL, White SN. Low-dose tretinoin does not improve striae distensae: A double-blind, placebo-controlled study. Cutis. 1994;54(2):121-124
12. Mallol J, Belda MA, Costa D, Noval A, Sola M. Prophylaxis of striae with a topical formulation. A double blind trial. Int J Cosmet Sci. 1991;13(1):51-57. doi:10.1111/j.1467-2494.1991.tb00547.x
13. Buchanan K, Fletcher HM, Reid M. Prevention of striae gravidarum with cocoa butter cream. International Journal of Gynecology & Obstetrics. 2009;108(1):65-68. doi:10.1016/j.ijgo.2009.08.008
14. Osman H. Usta IM, Rubeiz N, Abu-Ristum R, Charara I, et al. Cocoa butter lotion for prevention of striae gravidarum: A double-blind, randomized and placebo-controlled trial. BJOG. 2008;115(9):1138-1142. doi:10.1111/j.1471-0528.2008.01796.x
15. Davey CM. Factors associated with the occurrence of striae gravidarum. J Obstet Gynecol Br Commonw. 1972;79(12):1113-1114. doi:10.1111/j.1471-0528.1972.tb11896.x
16. Taavoni S, Soltanipour F, Haghani H, Ansarian H, Kheirkhah M. Effects of olive oil on striae gravidarum in the second trimester of pregnancy. Complementary Therapies in Clinical Practice. 2011;17(3):167-169. doi:10.1016/j.ctcp.2010.10.003
17. Soltanipoor F, Delaram M, Taavoni S, Haghani H. The effect of olive oil on prevention of striae gravidarum: A randomized controlled clinical trial. Complement Ther Med. 2012;20(5):263-266. doi:10.1016/j.ctim.2012.05.001
18. Ud-Din S, McAnelly SL, Bowring A, Whiteside S, Morris J, Chaudhry I, et al. A double-blind controlled clinical trial assessing the effect of topical gels on striae distensae (stretch marks): A non-invasive imaging, morphological and immunohistochemical study. Arch Dermatol Res. 2013;305(7):603-617. doi:10.1007/s00403-013-1336-7