Pencegahan Cerebral Palsy pada Asfiksia Neonatorum

Oleh :

dr.Saphira Evani

Beberapa intervensi diduga dapat mencegah cerebral palsy (CP) akibat asfiksia neonatorum. Asfiksia neonatorum menyebabkan hipoksia jaringan otak dan merupakan salah satu etiologi utama CP.

CP adalah kelainan gerak dan postur nonprogresif yang terjadi akibat gangguan saat proses perkembangan janin, proses persalinan, atau setelah kelahiran yang menyebabkan gangguan otak permanen. CP adalah penyebab utama disabilitas di usia anak-anak dan secara signifikan mempengaruhi kualitas hidup penderita dan juga keluarganya. [1]

Asfiksia neonatorum dilaporkan menyebabkan 45% neonatus meninggal dan 25% mengalami defisit neurologis CP dengan atau tanpa retardasi mental, sisanya mengalami gangguan penglihatan, pendengaran, dan gangguan belajar. [2] Tinjauan Cochrane yang dipublikasikan pada tahun 2018 melaporkan bahwa ada beberapa intervensi yang dapat mencegah CP pada neonatus yang mengalami asfiksia. [3]

(Konten ini khusus untuk dokter. Registrasi untuk baca selengkapnya)

Referensi

1. Hromkova M, Dobrikova P, Letovancoca K, Slana M. Quality of life in parents of children with cerebral palsy. 2018. https://www.researchgate.net/publication/328314523_Quality_of_Life_in_Parents_of_Children_with_Cerebral_Palsy
2. Logica T, Riviere S, Holubiec MI, Castilla R, Barreto GE, Capani F. Metabolic changes following perinatal asphyxia: role of astrocytes and their interaction with neurons. Aging Neurosci. 2016;8:116. https://doi.org/10.3389/fnagi.2016.00116
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