Pengaruh Faktor Psikologis terhadap Refluks Berulang

Oleh :

dr.Soeklola Muliady SpKJ

Refluks laringofaring dan gangguan refluks gastroesofageal, dua jenis refluks yang umumnya terjadi secara berulang, seringkali berkomorbiditas dengan gangguan psikologis dan saling memengaruhi. Baik gejala refluks laringofaring (laryngopharyngeal reflux atau LPR) dan gangguan refluks gastroesofageal (gastroesophageal reflux disease atau GERD), sama-sama memengaruhi kondisi kesehatan fisik, menurunkan kualitas hidup serta memengaruhi kondisi psikologis seseorang.[1-7]

Prevalensi global dari LPR sendiri mencapai 34.4% dan untuk GERD mencapai 2.5% hingga 39.2%. Tidak jarang keduanya terjadi bersamaan, dilaporkan sekitar 47,9% hingga 60% pasien GERD mengalami LPR dan 71% pasien LPR mengalami GERD.[1,2,8]

Hubungan Antara Faktor Psikologis dengan Refluks Berulang

(Konten ini khusus untuk dokter. Registrasi untuk baca selengkapnya)

Referensi

1. Chen G, Kuang X, Wang X, Ye J, Ren M, et al. Psychological Factors, Lifestyles, and Habits of Patients with Laryngopharyngeal Reflux: A Multicenter Survey. B-ENT. 2023;19(3):170–4. http://www.b-ent.be/en/psychological-factors-lifestyles-and-habits-of-patients-with-laryngopharyngeal-reflux-a-multicenter-survey-161234
2. Wong MW, Bair MJ, Chang WC, Hsu CS, Hung JS, et al. Clinical and psychological characteristics in gastroesophageal reflux disease patients overlapping with laryngopharyngeal reflux symptoms. J Gastroenterol Hepatol. 2019;34(10):1720–6. https://onlinelibrary.wiley.com/doi/epdf/10.1111/jgh.14651
3. Vasant DH, Whorwell PJ. Gut-focused hypnotherapy for Functional Gastrointestinal Disorders: Evidence-base, practical aspects, and the Manchester Protocol. Neurogastroenterol Motil. 2019;31(8):e13573. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850508/
4. He M, Wang Q, Yao D, Li J, Bai G. Association Between Psychosocial Disorders and Gastroesophageal Reflux Disease: A Systematic Review and Meta-analysis. J Neurogastroenterol Motil. 2022 Apr 30;28(2):212–21. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8978133/
5. Guadagnoli L, Geeraerts A, Geysen H, Pauwels A, Vanuytsel T, et al. Psychological Processes, Not Physiological Parameters, Are Most Important Contributors to Symptom Severity in Patients With Refractory Heartburn/Regurgitation Symptoms. Gastroenterology. 2023 Oct 1;165(4):848–60.
6. Hu J. Clinical and Psychological Features of Overlapping Dyspepsia in Gastroesophageal Reflux Disease. In: Proceedings of the 2nd International Symposium on Artificial Intelligence for Medicine Sciences. New York, NY, USA: Association for Computing Machinery; 2021. p. 199–203. (ISAIMS ’21). https://doi.org/10.1145/3500931.3500966
7. Mahoney LB, Rosen R. The Spectrum of Reflux Phenotypes. Gastroenterol Hepatol. 2019 Dec;15(12):646–54. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6935024/
8. Chandran S, Raman R, Kishor M, Nandeesh HP. The effectiveness of mindfulness meditation in relief of symptoms of depression and quality of life in patients with gastroesophageal reflux disease. Indian J Gastroenterol. 2019 Feb 1;38(1):29–38.
9. Li X, Ding F, Luo P, Yang J, Liu Z, et al. Study on the therapeutic effects of drug and cognitive-behavioral therapy on non-erosive reflux disease patients with emotional disorders. Front Psychiatry. 2018 May; 9. Available form: https://doi.org/10.3389/fpsyt.2018.00115
10. Yadlapati R. Approach to Management of Refractory Gastroesophageal Reflux Disease. Gastroenterol Hepatol. 2023 Aug;19(8):499–502. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10524426/
11. Yadlapati R, Gyawali CP, Pandolfino JE, Chang K, Kahrilas PJ, et al. AGA Clinical Practice Update on the Personalized Approach to the Evaluation and Management of GERD: Expert Review. Clin Gastroenterol Hepatol. 2022 May 1;20(5):984-994.e1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9838103/
12. Popa SL, Chiarioni G, David L, Dumitrascu DL. The Efficacy of Hypnotherapy in the Treatment of Functional Dyspepsia. Am J Ther. 2019 Dec;26(6):e704.
13. Glasinovic E, Wynter E, Arguero J, Ooi J, Nakagawa K, et al. Treatment of supragastric belching with cognitive behavioral therapy improves quality of life and reduces acid gastroesophageal reflux. Off J Am Coll Gastroenterol ACG. 2018 Apr;113(4):539.