Penggunaan Platelet-Rich Plasma pada Wanita dengan Alopecia Androgenetik

Oleh :

dr. Novianti Rizky Reza, Sp.KK

Platelet-rich plasma (PRP) telah banyak diteliti untuk penanganan kondisi dermatologis, termasuk alopecia androgenetik pada wanita. Alopecia androgenetik merupakan penyakit kerontokan rambut yang dipengaruhi oleh hormon androgen dan faktor genetik. Sebanyak 40% wanita usia 50 tahun dan 57% wanita usia 80 tahun mengalami alopecia androgenetik.[1]

Pilihan pengobatan alopecia androgenetik meliputi minoxidil, finasteride, spironolactone, dan terapi cahaya. Meski demikian, pemakaian modalitas tersebut memerlukan durasi terapi yang panjang untuk mencapai dan mempertahankan hasil yang optimal. Di sisi lain, tindakan transplantasi rambut memerlukan biaya yang cukup tinggi. PRP merupakan alternatif potensial untuk penanganan alopecia androgenetik pada wanita.[1,2]

Peran Penggunaan Platelet Rich Plasma dalam Penatalaksanaan Alopecia Androgenetik

(Konten ini khusus untuk dokter. Registrasi untuk baca selengkapnya)

Referensi

1. Mercuri SR, Paolino G, Di Nicola MR, Vollono L. Investigating the safety and efficacy of platelet-rich plasma (PRP) treatment for female androgenetic alopecia: Review of the literature. Medicina. 2021;57(4):311.
2. Stevens J, Khetarpal S. Platelet-rich plasma for androgenetic alopecia: a review of the literature and proposed treatment protocol. International journal of women’s dermatology. 2019;5(1):46–51.
3. Paichitrojjana A, Paichitrojjana A. Platelet Rich Plasma and Its Use in Hair Regrowth: A Review. Drug Des Devel Ther. 2022 Mar 10;16:635–45.
4. Justicz N, Chen JX, Lee LN. Platelet-Rich Plasma for Hair Restoration. In: Lee LN, editor. Hair Transplant Surgery and Platelet Rich Plasma [Internet]. Cham: Springer International Publishing; 2020 [cited 2022 Jun 2]. p. 113–21. http://link.springer.com/10.1007/978-3-030-54648-9_11
5. Ranasinghe GC, Bergfeld WF. PRP in Combination Therapy for Hair Loss (AGA). In: Aesthetic Clinician’s Guide to Platelet Rich Plasma. Springer; 2021. p. 53–70.
6. Abdin R, Zhang Y, Jimenez JJ. Treatment of Androgenetic Alopecia Using PRP to Target Dysregulated Mechanisms and Pathways. Frontiers in Medicine. 2022;9.
7. Zhou S, Qi F, Gong Y, Zhang C, Zhao S, Yang X, He Y. Platelet-Rich Plasma in Female Androgenic Alopecia: A Comprehensive Systematic Review and Meta-Analysis. Front Pharmacol. 2021 May 6;12:642980. doi: 10.3389/fphar.2021.642980.
8. Roohaninasab M, Goodarzi A, Ghassemi M, Sadeghzadeh‐Bazargan A, Behrangi E, Najar Nobari N. Systematic review of platelet‐rich plasma in treating alopecia: Focusing on efficacy, safety, and therapeutic durability. Dermatologic Therapy. 2021;34(2). https://onlinelibrary.wiley.com/doi/10.1111/dth.14768
9. Hesseler MJ, Shyam N. Platelet-Rich Plasma and Its Utilities in Alopecia: A Systematic Review. Dermatol Surg. 2020 Jan;46(1):93–102.
10. Ragab SEM, Nassar SO, Morad HA, Hegab DS. Platelet-rich plasma in alopecia areata: intradermal injection versus topical application with transepidermal delivery via either fractional carbon dioxide laser or microneedling. Acta Dermatovenerologica Alpina, Pannonica et Adriatica. 2020;29(4):169–76.
11. Ishii L, Lee LN. Techniques for hair restoration, an issue of facial plastic surgery clinics of North America. Vol. 28. Elsevier Health Sciences; 2020.