Manfaat Povidone Iodine untuk Sakit Tenggorokan

Oleh :

dr. Jocelyn Prima Utami

Sakit tenggorokan akibat infeksi saluran pernapasan atas (ISPA) sering diterapi dengan povidone iodine. Hal ini dikarenakan povidone iodine (PVP-I) adalah kompleks yang larut dalam air, di mana povidone bekerja sebagai molekul carrier iodine yang memiliki aktivitas antimikroba. Mayoritas kasus ISPA disebabkan oleh virus, seperti adenovirus, rhinovirus, influenza, respiratory simplex virus, hingga coronavirus sehingga cukup diterapi secara simtomatis.[1-6]

ISPA terjadi karena adanya penempelan dan kolonisasi dari patogen-patogen di mukosa saluran pernapasan. Gejalanya meliputi rhinorrhea, obstruksi nasal, laringitis, batuk, demam, dan sakit tenggorokan. Beberapa cara dikatakan dapat membantu mengurangi infeksi dan mengeradikasi patogen di saluran pernapasan, salah satunya adalah berkumur, baik dengan air putih, maupun dengan povidone iodine.

Penggunaan Povidone Iodine untuk ISPA

(Konten ini khusus untuk dokter. Registrasi untuk baca selengkapnya)

Referensi

1. Thomas M, Bomar PA. Upper Respiratory Tract Infection. In: Statpearls. Treasure Island (FL): Statpearls Publishing; 2024.
2. Centers for Disease Control and Prevention. Rhinoviruses. CDC; 2023. https://www.cdc.gov/ncird/rhinoviruses-common-cold.html
3. Worrall G. Common cold. Can Fam Physician. 2011 Nov;57(11):1289-90.
4. Addey D, Shephard A. Incidence, causes, severity and treatment of throat discomfort: a four-region online questionnaire survey. BMC Ear, Nose and Throat Disorders. 2012 Dec;12(1):1-0.
5. Kanagalingam J, Feliciano R, Hah JH, Labib H, Le TA, Lin JC. Practical use of povidone‐iodine antiseptic in the maintenance of oral health and in the prevention and treatment of common oropharyngeal infections. International journal of clinical practice. 2015 Nov;69(11):1247-56.
6. Meneghetti A, Mosenifar Z. Upper Respiratory Tract Infection. Medscape; 2020 Sep 11. https://emedicine.medscape.com/article/302460-overview
7. Allan GM, Arroll B. Prevention and treatment of the common cold: making sense of the evidence. Cmaj. 2014 Feb 18;186(3):190-9.
8. Eggers M, Koburger-Janssen T, Eickmann M, Zorn J. In vitro bactericidal and virucidal efficacy of povidone-iodine gargle/mouthwash against respiratory and oral tract pathogens. Infectious diseases and therapy. 2018 Jun;7:249-59.
9. Barreto R, Barrois B, Lambert J, Malhotra-Kumar S, Santos-Fernandes V, Monstrey S. Addressing the challenges in antisepsis: focus on povidone iodine. International journal of antimicrobial agents. 2020 Sep 1;56(3):106064.
10. Lepelletier D, Maillard JY, Pozzetto B, Simon A. Povidone iodine: properties, mechanisms of action, and role in infection control and Staphylococcus aureus decolonization. Antimicrobial agents and chemotherapy. 2020 Aug 20;64(9):10-128.
11. Quek AML, Ng MY, Teng O, Lim NA, Ng GJL, Yang SP, Hartman M, Tambyah PA, Cook AR, Seet RCS. Stable thyroid function despite regular use of povidone-iodine throat spray for SARS-CoV-2 prophylaxis. Ann Med. 2022 Dec;54(1):3299-3305.
12. Anderson DE, Sivalingam V, Kang AE, Ananthanarayanan A, Arumugam H, Jenkins TM, Hadjiat Y, Eggers M. Povidone-iodine demonstrates rapid in vitro virucidal activity against SARS-CoV-2, the virus causing COVID-19 disease. Infectious diseases and therapy. 2020 Sep;9(3):669-75.