Comparative Effectiveness of Budesonide/Formoterol Combination and Fluticasone/Salmeterol Combination Among Chronic Obstructive Pulmonary Disease Patients New to Controller Treatment: A US Administrative Claims Database Study

Kern DM, et al. Comparative effectiveness of budesonide/formoterol combination and fluticasone/salmeterol combination among chronic obstructive pulmonary disease patients new to controller treatment: a US administrative claims database study. Respiratory Research. 2015;16(1):52. PMID: 25899176.

Abstrak

Latar belakang: kombinasi kortikosteroid bersama long-acting β-2 agonist (ICS/LABA) inhalasi telah menjadi terapi lini pertama untuk pasien penyakit paru obstruktif kronis (PPOK) dengan riwayat eksaserbasi. Namun, belum ada percobaan klinis acak yang membandingkan exacerbation rate pada pasien PPOK yang mendapatkan kombinasi budesonide/formoterol (BFC) dan fluticasone propionate/salmeterol (FSC).