Faktor-faktor yang Meningkatkan Kualitas Non-invasive Prenatal Testing

Oleh :

dr. Michael Sintong Halomoan

Kualitas hasil non-invasive prenatal testing (NIPT) sebagai metode skrining kelainan genetik janin dapat ditingkatkan melewati berbagai faktor. Metode NIPT merupakan inovasi dalam bidang diagnostik prenatal yang menggunakan darah ibu untuk menentukan abnormalitas kromosom fetus. Pemeriksaan ini sangat benefisial, terutama bagi kelompok dengan risiko tinggi kelainan kongenital untuk mempersiapkan persalinan dan manajemen lanjut postpartum.

Sekilas Mengenai Non-Invasive Prenatal Testing

Non-invasive prenatal testing (NIPT) telah diperkenalkan secara luas di Amerika Serikat pada 2011 dan telah digunakan dalam skala global sejak 2018. Pemeriksaan ini menggunakan cell-free fetal DNA (cffDNA) yang beredar dalam darah ibu, yang berasal dari sel trofoblas plasenta.[1,2,9]

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Referensi

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