Rhinitis Alergi akibat Polusi dalam Ruangan

Oleh :

dr.Saphira Evani

Sudah banyak studi menunjukkan kaitan antara polusi dalam ruangan dengan penyakit alergi pada traktus respiratorius, salah satunya rhinitis alergi. Dilaporkan bahwa adanya polusi udara dapat berinteraksi dengan berbagai alergen airborne, sehingga meningkatkan risiko sensitisasi alergi dan mengeksaserbasi gejala pada pasien yang sudah memiliki alergi.[1]

Polusi Udara Dalam Ruangan

Polusi udara dalam ruangan adalah adanya kontaminan kimia, fisik, dan biologi pada udara dalam ruangan (misalnya: rumah dan kantor). Environmental Protection Agency (EPA) menilai kualitas udara dalam ruangan (indoor air quality) berdasarkan konsentrasi polutan dan kondisi termal (temperatur dan kelembapan relatif) yang mempengaruhi kesehatan, kenyamanan, dan performa kerja.[2]

Beberapa sumber polusi di dalam ruangan antara lain :

(Konten ini khusus untuk dokter. Registrasi untuk baca selengkapnya)

Referensi

1. Baldacci S, Maio S, Cerrai S, Sarno G, Baiz N, Simoni M, et al. Allergy and asthma: effects of the exposure to particulate matter and biological allergens. Respiratory Medicine. 2015;109:1089-1104. https://www.resmedjournal.com/article/S0954-6111(15)00187-0/pdf
2. Padilla RP, Schilmann A, Rodriquez HR. Respiratory health effects of indoor air pollution. Int J Tuberc Lung Dis 14(9):1079-1086. https://www.ingentaconnect.com/content/iuatld/ijtld/2010/00000014/00000009/art00003
3. Apte K, Salvi S. Household air pollution and its effects on health. F1000Res. 2016;5:F1000 Faculty Rev-2593. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089137/
4. Pawankar R. Allergic diseases and asthma: a global public health concern and a call to action. Pawankar World Allergy Organization Journal 2014, 7:12. http://www.waojournal.org/content/7/1/12
5. WHO. WHO Guidelines for Indoor Air Quality: Household Fuel Combustion. Geneva: World Health Organization; 2014. https://apps.who.int/iris/bitstream/handle/10665/141496/9789241548885_eng.pdf?sequence=1
6. Padilla RP, Schilmann A, Rodriquez HR. Respiratory health effects of indoor air pollution. Int J Tuberc Lung Dis 14(9):1079-1086. https://www.ingentaconnect.com/content/iuatld/ijtld/2010/00000014/00000009/art00003
7. Breysse PN, Diette GB, Matsui EC, et al. Indoor Air Pollution and Asthma in Children. Proc Am Thorac Soc, 2010. 7: 102-106.
8. Piekarska B, Sybilski AJ, Krzych‐Fałta E, et al. Effect of indoor air quality on the development of rhinitis in an urban population in Poland. Allergy and Asthma Proceedings, 2018. 39(6): e71–e77. doi:10.2500/aap.2018.39.4177
9. Annesi-Maesano I, Hulin M, Lavaud F, et al. Poor air quality in classrooms related to asthma and rhinitis in primary schoolchildren of the French 6 Cities Study. Thorax, 2012. 67(8): 682–688. doi:10.1136/thoraxjnl-2011-200391
10. Celedón JC, Milton DK, Ramsey CD, et al. Exposure to dust mite allergen and endotoxin in early life and asthma and atopy in childhood. Journal of Allergy and Clinical Immunology, 2007. 120(1): 144–149. doi:10.1016/j.jaci.2007.03.037
11. Greissner WA. Onset of action for the relief of allergic rhinitis symptoms with second-generation antihistamines. Allergy Asthma Proc, 2004; 25(2):81-3
12. Berkowitz RB, Woodworth GG, Lutz C, et al. Onset of action, efficacy, and safety of fexofenadine 60 mg/pseudoephedrine 120 mg versus placebo in the Atlanta allergen exposure unit. Annals of Allergy, Asthma & Immunology, 2002. 89(1): 38–45. doi:10.1016/s1081-1206(10)61909-6
13. Ciprandi G, Cosentino C, Milanese M, Mondino C, Canonica GW. Fexofenadine reduces nasal congestion in perennial allergic rhinitis. Allergy. 2001;56:1068-1070.
14. Lehman JM, Blaiss MS. Selecting the Optimal Oral Antihistamine for Patients with Allergic Rhinitis. Drugs, 2006. 66(18): 2309-2319.
15. Chen QY, Li L, Zhang L, Mo JH, Yang ZF, Wei XL, et al. Efficacy of indoor air purification in treating Artemisia (mugwort) pollen allergic rhinitis: a study protocol for a randomised controlled trial. BMC Public Health. 2018;18:841. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034272/#CR15
16. Sheikh A, Hurwitz B. House dust mite avoidance measures for perennial allergic rhinitis: a systematic review of efficacy. Brit Jour Gen Prac. 2003;53:318-322. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1314576/pdf/12879834.pdf
17. Vallance G, McSharry C, Wood S, Thomson NC. House dust mite control measures in the treatment of asthma. Ther Clin Risk Manag. 2006;2(4):347-54.