Kombinasi Lidokain-Bikarbonat Untuk Mengurangi Nyeri Prosedural Saat Anestesi Lokal

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Sunita

Kombinasi lidokain dengan bikarbonat diduga bermanfaat dalam mengurangi nyeri prosedural saat anestesi lokal. Anestesi lokal sering dilakukan pada tindakan minor seperti eksplorasi, desinfeksi, dan menjahit luka. Anestesi lokal juga digunakan untuk mengurangi nyeri pada prosedur tertentu, seperti pungsi lumbal dan kanulasi intravena.

Perbedaan pH antara larutan anestesi lokal dengan permukaan kulit diduga berperan terhadap timbulnya rasa nyeri atau sensasi tidak nyaman pada infiltrasi anestesi lokal. Meningkatkan pH anestesi lokal, atau buffering, diduga dapat meminimalkan rasa nyeri yang muncul.

Buffering dapat dilakukan terhadap berbagai anestesi lokal, seperti lidokain, bupivacaine, ropivacaine dan mepivacaine, serta articaine. Larutan buffer yang umum digunakan adalah natrium bikarbonat, serta dinatrium fosfat ditambah natrium bikarbonat.[1,2]

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Referensi

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