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Indikasi dan Dosis Koenzim Q10
Indikasi koenzim Q10 mencakup defisiensi koenzim Q10, fibromyalgia, gagal jantung, hipertensi, miopati karena statin, diabetes, penyakit neurodegeneratif, dan kanker. Belum ada dosis koenzim Q10 yang disepakati secara global. Rentang dosis yang biasa digunakan adalah 300 mg/hari.[14-38]
Defisiensi Koenzim Q10
Defisiensi koenzim Q10 terdiri dari defisiensi primer dan sekunder. Defisiensi primer terjadi karena mutasi pada gen yang terlibat dalam sintesis enzim koenzim Q10, sedangkan defisiensi sekunder terjadi karena mutasi pada gen yang tidak langsung berkaitan dengan biosintesis koenzim Q10 atau faktor non genetik.
Referensi
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