Penatalaksanaan Gonorrhea

Oleh :

dr. Erika Gracia

Penatalaksanaan gonorrhea atau gonore adalah antibiotik yang umumnya diberikan pada kunjungan pertama. Identifikasi dan pengobatan pasangan pasien juga penting untuk mencegah infeksi ulang dan komplikasi.[15]

Terapi Medikamentosa Antibiotik

Antibiotik merupakan terapi utama untuk orang dewasa dan remaja dengan infeksi gonore genital, anorektal, maupun orofaringeal. Berdasarkan WHO tahun 2024, rekomendasi antibiotik adalah:

Referensi

2. Qureshi S. Gonorrhea: Practice Essentials, Background, Pathophysiology. Medscape, 2021. https://emedicine.medscape.com/article/218059-overview#a1
4. St. Cyr S et al. Update to CDC’s Treatment Guidelines for Gonococcal Infection. Morb Mortal Wkly Rep. 2020 Dec 18;69(50):1911–6.
9. Fifer H et al. 2018 UK national guideline for the management of infection with Neisseria gonorrhoeae. Int J STD AIDS. 2020 Jan;31(1):4-15. doi: 10.1177/0956462419886775. PMID: 31870237.
15. Suay-García B, Pérez-Gracia MT. Future Prospects for Neisseria gonorrhoeae Treatment. Antibiotics. 2018 Jun 15;7(2):49.
16. WHO. Updated recommendations for the treatment of Neisseria gonorrhoeae, Chlamydia trachomatis, and Treponema pallidum (‎syphilis)‎ and new recommendations on syphilis testing and partner services. 2024. https://www.who.int/publications/i/item/9789240090767
17. Brittain C et al. Gentamicin versus ceftriaxone for the treatment of gonorrhoea (G-TOG trial): study protocol for a randomised trial. Trials 2016; 17:558.
18. Quaye N, Cole MJ, Ison CA. Evaluation of the activity of ertapenem against gonococcal isolates exhibiting a range of susceptibilities to cefixime. J Antimicrob Chemother 2014; 69:1568.
19. Eyre DW et al. Gonorrhoea treatment failure caused by a Neisseria gonorrhoeae strain with combined ceftriaxone and high-level azithromycin resistance, England, February 2018. Euro Surveill 2018; 23.
20. Unemo M, Nicholas RA. Emergence of multidrug-resistant, extensively drug-resistant and untreatable gonorrhea. Future Microbiol 2012; 7:1401.
21. Bolan G, Weinstock HS. Neisseria gonorrhoeae antimicrobial resistance among men who have sex with men and men who have sex exclusively with women: the Gonococcal Isolate Surveillance Project, 2005-2010. Ann Intern Med. 2013;158(5 Pt 1):321.
22. CDC. Gonorrhea Treatment. 2022. https://www.cdc.gov/std/gonorrhea/treatment.htm
23. Workowski KA, Bachmann LH, Chan PA, et al. Sexually Transmitted Infections Treatment Guidelines, 2021. MMWR Recomm Rep 2021; 70:1.
24. Erbelding EJ, Zenilman JM. Toward better control of sexually transmitted diseases. N Engl J Med 2005; 352:720.

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