Diagnosis Hepatitis A

Oleh :

dr. Jocelyn Prima Utami

Diagnosis hepatitis A ditegakkan secara klinis melalui tanda dan gejala jaundice, disertai keluhan infeksi viral lainnya, seperti mual, muntah, demam, dan lemas. Diagnosis pasti berdasarkan pemeriksaan antibodi anti-HAV. Infeksi virus hepatitis A (HAV) di area endemis seringkali asimtomatik akibat paparan virus saat anak-anak.[1,2]

Anamnesis

Masa inkubasi infeksi hepatitis A umumnya 14−28 hari. Infeksi HAV akut umumnya self-limited, yang diawali dengan fase prodromal dan diikuti dengan fase ikterik.[1,2,14]

Referensi

1. Iorio N, John S. Hepatitis A. In: Stat Pearls. Treasure Island (FL): StatPearls Publishing; 2021 Jan. https://www.ncbi.nlm.nih.gov/books/NBK459290/
2. Gilroy RK. Hepatitis A. Medscape. 2019 May. https://emedicine.medscape.com/article/177484-overview#a2
3. Setyowati D, Mubawadi T, Mirasa YA, et al. Molecular epidemiology of hepatitis A outbreaks in two districts in Indonesia in 2018: Same subtype, but different strains. Biomed Rep. 2020;12(2):51-58. doi:10.3892/br.2019.1261
4. Shin EC, Jeong SH. Natural history, clinical manifestations, and pathogenesis of hepatitis A. Cold Spring Harbor perspectives in medicine. 2018 Sep 1;8(9):a031708.
10. Migueres M, Lhomme S, Izopet J. Hepatitis A: Epidemiology, High-Risk Groups, Prevention and Research on Antiviral Treatment. Viruses. 2021 Oct;13(10):1900.
14. Mohsen W, Levy MT. Hepatitis A to E: what's new?. Internal medicine journal. 2017 Apr;47(4):380-9.
15. Lin KY, Chen GJ, Lee YL, Huang YC, Cheng A, Sun HY, Chang SY, Liu CE, Hung CC. Hepatitis A virus infection and hepatitis A vaccination in human immunodeficiency virus-positive patients: A review. World journal of gastroenterology. 2017 May 28;23(20):3589.
16. Waqar S, Sharma B, Koirala J. Hepatitis E. In: Stat Pearls. Treasure Island (FL): StatPearls Publishing; 2022 Jan
17. Remy P, Widjaja D. Hepatitis E. Medscape. 2019 Mar. https://emedicine.medscape.com/article/178140-differential#1
18. Shah NJ, Royer A, John S. Alcoholic Hepatitis. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2021 Jan-.
19. Tripathi N, Mousa OY. Hepatitis B. In: Stat Pearls. Treasure Island (FL): StatPearls Publishing; 2021 Jan-.
20. Basit H, Tyagi I, Koirala J. Hepatitis C. In: Stat Pearls. Treasure Island (FL): StatPearls Publishing; 2021 Jan-.
21. Masood U, John S. Hepatitis D. In: Stat Pearls. Treasure Island (FL): StatPearls Publishing; 2021 Jan
22. Lanini S, Ustianowski A, Pisapia R, Zumla A, Ippolito G. Viral hepatitis: etiology, epidemiology, transmission, diagnostics, treatment, and prevention. Infectious Disease Clinics. 2019 Dec 1;33(4):1045-62.
23. Mehta N, Ozick LA. Drug Induced Hepatotoxicity. Medscape. 2019 May. https://emedicine.medscape.com/article/169814-overview#a1
24. Francis P, Navarro VJ. Drug Induced Hepatotoxicity. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2022 Jan

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Diagnosis Hepatitis A

Referensi

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